Nanoxis Consulting AB

Rational antibody design for undruggable targets using kinetically controlled biomolecular probes

Trkulja, C., Jungholm, O., Davidson, M., Jardemark, K., Marcus, M.M., Hägglund, J., Karlsson, A., Karlsson, R. Bruton, J., Ivarsson, N., Srinivasa, S.P., Cavallin, A., Svensson, P., Jeffries, G.D.M., Christakopoulou, M.-N., Reymer, A., Ashok, A., Willman, G., Papadia, D., Johnsson, E., Orwar, O.  Science Advances 7 (16), eabe6397 DOI: 10.1126/sciadv.abe6397 (2021).

Mass Spectrometry Proteotyping-Based Detection and Identification of Staphylococcus aureus, Escherichia coli, and Candida albicans in Blood.

Kondori, N., Kurtovic, A., Piñeiro-Iglesias, B., Salvà-Serra, F., Jaén-Luchoro, D., Andersson, B., Alves, G., Ogurtsov, A., Thorsell, A., Fuchs, J., Tunovic, T., Kamenska, N., Karlsson, A., Yu, Y.-K., Moore, E.R.B., Karlsson, R.Frontiers in Cellular and Infection Microbiology 11, 686 (2021).

Genomic and Proteomic Characterization of the Extended-Spectrum β-Lactamase (ESBL)-Producing Escherichia coli Strain CCUG 73778: A Virulent, Nosocomial Outbreak Strain.

Jaén-Luchoro, D., Busquets, A., Karlsson, R., Salvà-Serra, F., Åhrén, C., Karami, N., Moore, E.R.B.  Microorganisms 8(6):893 (2020).

A Pangenome Approach for Discerning Species-Unique Gene Markers for Identifications of Streptococcus pneumoniae and Streptococcus pseudopneumoniae.

Gonzales-Siles, L., Karlsson, R., Schmidt, P., Salvà-Serra, F., Jaén-Luchoro, D., Skovbjerg, S., Moore, E.R.B., Gomila, M.  Frontiers in Cellular and Infection Microbiology 10:222 (2020).

Identification of surface proteins in a clinical Staphylococcus haemolyticus isolate by bacterial surface shaving.

Wolden, R., Pain, M., Karlsson, R., Karlsson, A., Aarag Fredheim, E.G., & Cavanagh, J.P.  BMC Microbiology volume 20, Article number: 80 (2020).

Discovery of Species-unique Peptide Biomarkers of Bacterial Pathogens by Tandem Mass Spectrometry-based Proteotyping.

Karlsson, R., Thorsell, A., Gomila, M., Salvà-Serra, F., Jakobsson, H.E., Gonzales-Siles, L., Jaén-Luchoro, D., Skovbjerg, S., Fuchs, J., Karlsson, A., Boulund, F., Johnning, A., Kristiansson, E. Moore, E.R.B.  Molecular & Cellular Proteomics 19 (3) 518-528 (2020).

Proteotyping bacteria: Characterization, differentiation and identification of pneumococcus and other species within the Mitis Group of the genus Streptococcus by tandem mass spectrometry proteomics.

Karlsson, R., Gonzales-Siles, L., Gomila, M., Busquets, A., Salvà-Serra, F., Jaén-Luchoro, D., Jakobsson, H.E., Karlsson, A., Boulund, F., Kristiansson, E., Moore, E.R.B. PLoS One. 13(12):e0208804 (2018).

Proteomic analysis of enterotoxigenic Escherichia coli (ETEC) in neutral and alkaline conditions.

Gonzales-Siles, L., Karlsson, R., Kenny, D., Karlsson, A., Sjöling, Å.  BMC Microbiology 17:11 (2017).

Typing and Characterization of Bacteria Using Bottom-up Tandem Mass Spectrometry Proteomics.

Boulund, F., Karlsson, R., Gonzales-Siles, L., Johnning, A., Karami, N., Al-Bayati, O., Åhrén, C., Moore, E.R.B., Kristiansson, E.  Molecular and Cellular Proteomics. 16(6):1052-1063 (2017).

A communal catalogue reveals Earth’s multiscale microbial diversity.

11.Thompson, L. R. et al.  Nature volume 551, pages 457–463 (2017).

Comparative Analysis of Two Helicobacter pylori Strains using Genomics and Mass Spectrometry-Based Proteomics.

Karlsson, R., Thorell, K., Hosseini, S., Kenny, D., Sihlbom, C., Sjöling, Å., Karlsson, A., Nookaew, I. Frontiers in Microbiology. 2016 Nov 11;7:1757 (2016).

Proteotyping: Proteomic characterization, classification and identification of microorganisms - A prospectus

Karlsson, R., Gonzales-Siles, L., Boulund, F., Svensson-Stadler, L., Skovbjerg, S., Karlsson, A., Davidson, M., Hulth, S., Kristiansson, E. Moore, E.R.B.

Syst Appl Microbiol 2015 38(4): 246-257.

Subcellular localization of an ATPase in anammox bacteria using proteomics and immunogold electron microscopy

Karlsson R, Karlsson A, Bäckman O, Johansson BR, Hulth S.

FEMS Microbiology Letters 2014 354(1): 10-18.

Detection of ligand-receptor binding using microfluidic frontal affinity chromatography on proteoliposomes derived directly from native cell membranes

Olesen K, Karlsson R, Lind U, Davidson M, Blomberg A, Karlsson A.

Journal of Chromatography B 2013 931: 84-89.

Combining phenotypic and proteomic approaches to identify membrane targets in a ´triple negative´ breast cancer cell type

Rust S, Guillard S, Sachsenmeier K, Hay C, Davidson M, Karlsson A, Karlsson R, Brand E, Lowne D, Elvin J, Flynn M, Kurosawa G, Hollingsworth R, Jermutus L, Minter R

Mol Cancer 2013 12(11).

Microfluidic flow cell for sequential digestion of immobilized proteoliposomes

Jansson ET, Trkulja CL, Olofsson J, Millingen M, Wikström J, Jesorka A, Karlsson A, Karlsson R, Davidson M, Orwar O.

Anal Chem. 2012 Jul 3;84(13):5582-8. doi: 10.1021/ac300519q. Epub 2012 Jun 13.

Strain-level typing and identification of bacteria using mass spectrometry-based proteomics

Karlsson R, Davidson M, Svensson-Stadler L, Karlsson A, Olesen K, Carlsohn E, Moore ER.

J Proteome Res. 2012 May 4;11(5):2710-20. doi: 10.1021/pr2010633. Epub 2012 Apr 11.

Membrane protein profiling of human islets of Langerhans using several extraction methods

Hansson SF, Henriksson Å, Johansson L, Korsgren O, Eriksson JW, Tornqvist H, Davidsson P.

Clin. Proteom., 2010, 6(4), 195 - 207.

Improving the depth of coverage in membrane proteomic studies through the use of lipid-based protein immobilization technology in parallel with methanol-facilitated solubilisation

Padliya ND, Bhatia MB, Hofgärtner WT, Hariri RJ

Anal. Methods, 2010, 2, 539 - 545.

Elucidation of the outer membrane proteome of Salmonella enterica serovar Typhimurium utilising a lipid-based protein immobilization technique

Chooneea D, Karlsson R, Encheva V, Arnold C, Appleton H, Shah H.

BMC Microbiol., 2010, 10, 44.

Identification of key proteins involved in the anammox reaction

Karlsson R, Karlsson A, Bäckman O, Johansson BR, Hulth S.

FEMS Microbiology Letters, 2009, 297(1), 87 - 94.